A patent at the University of Samarra in the manufacture of a long-term sterilizer is the first of its kind in the world

 

In the series of qualitative achievements of the University of Samarra and the support of the President of the University, Prof. Dr. Sabah Allawi Al-Samarrai, for researchers at the university and its distinguished research teams, a patent was registered with the title:

(Long-term sterile preparation for external surfaces using green chemistry in light of the Corona crisis)

The study included the preparation of a new formula for the first time in the world to purify the external surfaces of microorganisms with high efficiency and long term. The procedure consisted of a binary mixture of surfactants from each of the anionic surfactants (Sodium dodecyl). sulfate (SDS)) and the cationic surface-active substance (Cetylpyridinium chloride (CPC)) in the presence of different nanomaterials diagnosed by (X-ray diffraction, Energy-dispersive X-rays, Atomic force microscope, Scanning electron microscope, Transmission electron microscope, UV- visible spectrum, Fourier-transform infrared spectrum, The Surface area analysis) and with specific concentrations and ratios prepared using green chemistry and in the presence of eucalyptus extract and at different temperatures (283.15-343.15 K), as the (viscosity) of the binary mixture was studied, and it was found that the highest value was at the ratio (2:8) of (3% wt) of each of (SDS) and (CPC) respectively, which indicates the formation of worm-or thread-like micelles, and that the viscosity increases significantly in the presence of Other additives, thermodynamic functions (∆G°, ∆H, ∆S°) as well as activation energy (Ea) were studied, and the results showed an increase in spontaneity, enthalpy, randomness and activation power with increasing concentrations of the prepared materials.

The results showed the ability of the mixture to inhibit the bacterium Bacillus pumilus with diameters of inhibition (14.7 mm) compared to (12.8 mm) for the antibiotic (Nystatin), as well as the ability to inhibit Candida albicans, which causes most cases of fungal infections in humans, with diameters of inhibition. (14.7 mm) compared to (20.09 mm) for Nystatin. They tested the time of the mixture remaining active on the external surfaces, as the results showed that no microorganism grew even after more than (7) days for culture media that were contaminated with three types of soil with the mixture compared to non-sterile culture media, which showed the growth of many microorganisms under the same conditions. They obtained pure isolates of microorganisms from the General Company for Drugs Industry’s biological efficacy laboratories and Medical Appliances Samarra -SDI. The examination protocol was according to the United States Pharmacopeia – USP.

Applications: Applications

1- The sterile can be used in the medical and pharmaceutical fields, such as sterilizing surfaces in health institutions such as hospitals and others, which are a place where many microorganisms gather.
2- The sterile can be used in other fields, such as sterilizing the surfaces of official departments and all gathering places such as airports, schools, sports stadiums, places of worship, etc.
3- It is used in the industrial field.
4- It is used to reduce environmental pollution and its spread.
5- It is used in research and applied fields.

Advantages :
1- It is an effective sterilizer against most microorganisms of all strains.
2- The period of its survival on surfaces increases effectively as the temperature decreases, as the time of the reduction in temperature is the appropriate time for the activity of most microbes, which makes it more effective at the height of the action of these organisms.
3- The sterilizer contains nanomaterials with light activity, as these materials work to kill and inhibit microorganisms with the least possible light, making it active even in non-luminous places.
4- The sterilizer contains surface-active substances that keep the spread of nanomaterials inside the sterilizer without clumping, which increases the effectiveness of the sterilizer, and the surface-active substances increase the biological decomposition of microorganisms.
5- The sterilizer contains activated charcoal particles with pores and a high surface area that helps keep the nanomaterials adsorbed on its surface for as long as possible, thus the length of the sterilizer’s effectiveness knowing that it was prepared straightforwardly and using green chemistry.
6- The production of activated charcoal inside our country at a low production cost.
7- The sterilizer contains low concentrations of nanomaterials, which makes its use safe. It also contains ethanol at a low concentration compared to traditional disinfectants that contain high concentrations.
8- The sterilizer contains eucalyptus leaf extract, which significantly increases the effectiveness and viscosity of the sterilizer.
9- It can be prepared quickly and with available and straightforward materials, at a low cost and in a short time, as the materials used in its preparation are available in almost any country in the world.
The formula used to prepare the sterilizer is the first of its kind globally, and it can be applied currently in light of the Corona crisis.

On this occasion, the President of the University expressed his heartfelt thanks for the distinguished research team activity consisting of
1- Prof. Liqa’a Hussein Alwan
2- Dr. Iman Diab Ahmed
3- Prof. Anwar Ahmed Mohamed
4- Basem Fadel Mahmoud

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