Chemistry Department Discusses Master’s Thesis on the Quantitative Determination of Some Antidiabetic Drugs Using Different Analytical Methods

 

The Department of Chemistry at the College of Education for Pure Sciences, University of Samarra, discussed a master’s thesis entitled: “Quantitative Determination of Some Antidiabetic Drugs Using Different Analytical Methods.”

The thesis, presented by student Khudhur Ahmed Mohammed, aimed to develop modern, sensitive, and accurate spectroscopic and chromatographic analytical methods for the determination of two antidiabetic pharmaceutical compounds, namely Metformin Hydrochloride and Empagliflozin, in their pure forms as well as in pharmaceutical preparations.

The results showed that the optimum reagent volume was 0.5 mL. They also indicated that a temperature of 30°C was the optimum condition for obtaining the highest absorbance of the colored product. Furthermore, the second-derivative spectroscopic measurement demonstrated a clear separation of the absorption peaks of each drug individually and in their mixture, contributing to improved accuracy in quantitative determination and analysis.

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