A master’s thesis at the University of Samarra examines the evaluation of certain biochemical, physiological, and molecular parameters in kidney failure patients.
The thesis, presented by the student Ansam Hassan Alwan at the College of Applied Sciences, University of Samarra, is titled: “Evaluation of Certain Biochemical, Physiological, and Molecular Parameters in Kidney Failure Patients in Salahuddin.”
The aim of the study was to assess the effects of antioxidants and oxidative stress markers (SOD and MDA) using the ELISA test, as well as to investigate the polymorphisms of the SOD1 and SOD2 genes. Additionally, it sought to study the genes influencing the metabolic pathways of these compounds and identify variations in gene sequences associated with kidney failure.
The findings revealed elevated levels of antioxidants in the patient group compared to the healthy group. Furthermore, mutant and normal alleles were identified in both groups, along with the discovery of genetic mutations in the SOD1 and SOD2 genes in both patients and healthy individuals.
