The Dissertation of Lecturer Hammam Izzat Receives a “Pass” Evaluation After Defense at the College of Education for Pure Sciences

The PhD dissertation of Lecturer Hammam Izzat Mohammed, a faculty member in the Department of Pathological Analyses at the College of Applied Sciences, University of Samarra, was awarded a “Pass” evaluation in the field of Chemistry following its defense at the College of Education for Pure Sciences at the same university.

The dissertation was entitled:
“Evaluation of the Sensitivity and Specificity of Glial Fibrillary Acidic Protein (GFAP) and Selected Biochemical Parameters as Diagnostic Biomarkers for Multiple Sclerosis.”

In this context, the researcher aimed to investigate the diagnostic value of both GFAP and neurofilament light chain (NfL), in addition to several neurological markers, oxidative stress parameters, and lipid profile indices. The study sought to enhance the accuracy of early diagnosis of multiple sclerosis and to better understand the pathological mechanisms associated with neurodegeneration and disability progression.

In conclusion, the findings demonstrated a significant increase in the levels of GFAP, NfL, catalase enzyme, total cholesterol, triglycerides, and low-density lipoproteins (LDL) in patients compared to the control group. Conversely, levels of Vitamin D3 and activating transcription factor 3 (ATF3) were significantly decreased, supporting the potential use of these biomarkers as complementary tools in diagnosis and clinical follow-up.