A Faculty Member from the College of Education for Pure Science Publishes a Research Paper in Scopus
Dr. Mohammed Mahmood Abdullah, a faculty member in the Department of Chemistry at the College of Education for Pure Sciences, University of Samarra, has published a scientific research paper in ELSVIER Journal, which is classified as a Q2 journal in the Scopus database. The paper is titled “Computational Design and Characterization of Arginine-Functionalized ZIF-8 as a pH-Responsive Oral Insulin Carrier.”
In his research, Dr. Mahmood aimed to assess the structural and energetic feasibility of this system as an intelligently designed, pH-responsive oral delivery platform, in addition to evaluating arginine-modified ZIF-8 (ZIF-8@Arg) as a potential system for oral insulin delivery.
The study’s results demonstrated improved binding stability at the ZIF-8@Arg–insulin interface, as well as pH-dependent structural adaptability. Furthermore, computational analysis of absorption, distribution, metabolism, excretion, and toxicity (ADMET) indicated reduced predicted toxicity and compatibility with oral administration.
