A master’s thesis at Samarra University discusses the efficient preparation, characterization, and biological applications of certain compounds containing the oxazepine nucleus.
A master’s thesis in the College of Education at Samarra University, titled “Efficient Preparation, Characterization, and Biological Applications of Some Compounds Containing the Oxazepine Nucleus,” was presented by student Mohammed Abdulrazzaq Mohammed.
In his thesis, the student aimed to study heterocyclic compounds in the fields of medicine and pharmacy, as well as various applications in synthesizing pharmaceutical compounds with broad-spectrum antibiotic activity. The research involved the preparation of Schiff bases derived from 4,4-diaminodiphenylmethane, the synthesis of cyclic imide derivatives, and the creation of new oxazepine ring derivatives from Schiff bases.
The study results indicated that the “2.50 ppm” signal corresponded to the solvent (DMSO-d6), a single peak at “3.41 ppm” corresponded to the protons of the (H2O) group, a signal at “3.97 ppm” corresponded to the (CH2) protons in the compound, and single signals at “6.58 – 6.70 ppm” were attributed to the (C-H) protons of the furan ring. The IR spectrum of the oxazepine compounds prepared from Schiff bases showed absorption bands in the “3055-3028 cm-1” range, which were attributed to the stretching of the aromatic (C-H) bond in compounds (M28-M11).
