Master’s Thesis at the University of Samarra Discusses the Relationship Between Certain Antimicrobial Peptides and Escherichia coli
A master’s thesis was discussed at the College of Applied Sciences, University of Samarra, titled “A Study on the Relationship Between Certain Antimicrobial Peptides and Escherichia coli Bacteria Causing Urinary Tract Infections in Children Under Five Years Old,” by the student Hala Wameed Kamal.
The student aimed to determine the role of specific peptide-based antimicrobials in innate immunity during urinary tract infections caused by Escherichia coli in children under five.
The results indicated that individuals infected with Escherichia coli had higher concentrations of hepcidin in their urine (1234.8 ± 86) and serum (563 ± 547) compared to other bacterial types, where its levels were (545 ± 106) in urine and (468.3 ± 75.5) in serum. The findings also showed that hepcidin levels were higher in urine (795 ± 226.8) compared to serum (106.3 ± 544.7) in those infected with E. coli. Additionally, ferritin levels (11.2 ± 0.9) and iron (39 ± 7) were lower in infected individuals compared to healthy individuals.
