Ph.D. Dissertation at the University of Samarra Explores a Comparative Study on the Evaluation of Vitamin A and B Levels in Patients with Beta Thalassemia

A Ph.D. dissertation at the College of Education, University of Samarra, titled “A Comparative Study to Evaluate the Levels of Vitamins A and B and Some Biochemical Indicators as Markers of Liver Damage in Patients with Beta Thalassemia,” was presented by researcher (Maher Rashid Hamid).

In his dissertation, the researcher aimed to assess the levels of vitamins A and B, as well as certain inflammatory cytokines, specifically Interleukin-33 (IL-33) and Interferon-alpha (IFN-α), in patients with beta thalassemia. He also evaluated several biochemical variables, including metallopeptidase enzyme, ferritin, iron, hemoglobin, in addition to assessing the activity of liver enzymes such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase.

Rashid found a significant increase in the levels of vitamins A and B in patients with major beta thalassemia compared to the healthy control group. There was also a significant rise in the levels of the inflammatory cytokines (IL-33 and IFN-α) in these patients, along with elevated levels of the biochemical variables and increased activity of liver enzymes.